Gavi, 19, will undergo tests on Monday to determine the full severity of the injury, but sources close to the player fear he could be set for a lengthy spell on the sidelines.
Gavi was able to limp off the pitch with Spain’s medical staff, but the expression on his face suggested he feared the worst.
The Spain players also seemed aware of the extent of the injury, with Barça teammate Ferran Torres celebrating his goal, which made it 2-1, by holding up Gavi’s No.9 shirt.
Gavi has been a a regular for Barça and Spain this season, only missing two games — both for his club — through suspension.
Pedri returned to action just before the international break after two months out, with De Jong in line to make his comeback against Rayo Vallecano this weekend.
Spain had already booked their place at next summer’s Euro 2024 finals in Germany prior to Sunday’s match against Georgia, but still ended their qualifying campaign with a win at the José Zorrilla Stadium in Valladolid.
Torres restored Spain’s lead in the 55th minute and Lochoshvili completed the scoring, heading youngster Lamine Yamal‘s cross into his own net with just under 20 minutes remaining.